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Ultra Cell Biotect

60 day supply: $91.00
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  • Features
  • Details
  • Supplement Facts
  • Related Info
  • A blend of plant extracts containing unique phytochemicals that complement our natural antioxidant defenses by neutralizing free radicals.
    • Greenselect® Phytosome®: high absorption, caffeine-free green tea extract
    • Capsicum annuum (pepper) powder
    • Curcumin C3 Complex®: high absorption turmeric extract
    • Sirtmax®: Kaempferia parviflora (black turmeric) extract
    • Enovita®: European grape seed extract
  • Vegan
  • No gluten-containing ingredients
  • No genetically modified ingredients

Caution: If you are pregnant, nursing, or on medication, consult with your healthcare practitioner.

 

Ultra Cell Biotect contains unique phytochemicals from extracts of green tea, pepper (Capsicum annuum), turmeric, black turmeric (Kaempferia parviflora), and grape seed to complement a healthful diet and protect cellular health. Normal cellular metabolism produces byproducts that can age or damage our cells, such as free radicals. Dietary antioxidant phytochemicals complement our natural antioxidant defenses by neutralizing free radicals and affecting cell signaling pathways that promote cardiovascular health, the inflammatory response, proper cell growth, and cellular stability.

The green tea and turmeric extracts in Ultra Cell Biotect were selectively chosen because they have been formulated with complementary ingredients that enhance absorption. Capsicum annuum is included because of its potential synergy with green tea, grape seed for its rich concentration of proanthocyanidins, and Kaempferia parviflora for its potential to activate the SIRT1 pathway, which is thought to promote healthy aging.

Green tea

The leaves of the tea plant, Camellia sinensis, are rich in certain catechins, flavonoid antioxidants that are very rare in other plant foods. Green tea is especially rich in tea catechins, epigallocatechin 3-gallate (EGCG) in particular. Epidemiologic studies have found that drinking brewed green tea regularly is associated with cardiovascular health and longevity.1-9 In vitro studies (studies in cultured cells) suggest that green tea catechins work through a variety of mechanisms, including protecting healthy cells against oxidative damage and affecting signaling pathways that promote normal DNA repair and inflammatory status.10

Greenselect® Phytosome® is a caffeine-free green tea extract that uses sunflower lecithin to enhance absorption.11, 12 A human study comparing lecithin-complexed green tea to “free” green tea found that the peak EGCG concentration in plasma, which occurred 2 hours after ingestion, was 2-fold higher for lecithin-complexed green tea.11 A 24-week human study found that Greenselect® Phytosome® has antioxidant effects, and that it could help maintain healthy fasting glucose, triglycerides, and blood pressure.12

Capsicum annuum

Capsicum annuum is a species that includes many different varieties of peppers. In vitro, phytochemicals called vanilloids, which are present in Capsicum annuum have shown synergistic effects with green tea, magnifying the protective effects of green tea on cells.13

Curcumin & whole turmeric

Curcumin refers collectively to the major bioactive components (curcuminoids) of the turmeric root (Curcuma longa), a yellow-colored culinary spice: curcumin, bisdemethoxycurcumin, and demethoxycurcumin. In vitro, curcumin has been shown to inhibit NF-κB, a transcription factor and regulator of the inflammatory response.14-16

Although it is helpful to season foods with turmeric regularly, the benefits of dietary turmeric may be limited by curcumin’s poor bioavailability. Curcumin C3 Complex® is an extensively studied turmeric extract, which contains 95 percent curcuminoids and uses piperine (Bioperine®), a black pepper extract, to enhance absorption.17 For additional turmeric-derived phytochemicals to complement the curcuminoid-concentrated extract, whole turmeric is also included.

Research on curcumin complexed with piperine in humans suggests it has antioxidant effects, protects the cardiovascular system, supports joint health, and promotes a healthy inflammatory response.18-21

Kaempferia parviflora

Sirtmax® is an extract of Kaempferia parviflora (also known as black turmeric), a root related to turmeric and ginger. In vitro, Kaempferia parviflora phytochemicals activate the SIRT1 pathway and protect against oxidative damage.22, 23 Sirtmax® helps activate the SIRT1 enzyme to support healthy aging. Also, results of a seven-week placebo-controlled human study suggested that Sirtmax® helps to keep blood glucose in the healthy range and may also help to limit visceral fat accumulation.24

Grape seed extract

Grapes are a common food, but grapes with seeds are less common; grape polyphenols are concentrated in the seeds, skins, stems, and leaves, rather than in the flesh. When compared directly, the seeds have the greatest antioxidant capacity, followed by the leaf, skin, and then flesh. The major classes of antioxidant phytochemicals in grape seeds and skin are proanthocyanadins, and grape seeds are especially rich in these phytochemicals compared to other foods.25, 26 In a four month human trial, Enovita® grape seed extract was shown to have antioxidant effects and promote cardiovascular health.27

 
References
  1. Wang ZM, Zhou B, Wang YS, et al. Black and green tea consumption and the risk of coronary artery disease: a meta-analysis. The American journal of clinical nutrition 2011, 93:506-515.
  2. Arab L, Liu W, Elashoff D. Green and black tea consumption and risk of stroke: a meta-analysis. Stroke 2009, 40:1786-1792.
  3. Tang N, Wu Y, Zhou B, et al. Green tea, black tea consumption and risk of lung cancer: a meta-analysis. Lung Cancer 2009, 65:274-283.
  4. Sun CL, Yuan JM, Koh WP, Yu MC. Green tea, black tea and breast cancer risk: a meta-analysis of epidemiological studies. Carcinogenesis 2006, 27:1310-1315.
  5. Ogunleye AA, Xue F, Michels KB. Green tea consumption and breast cancer risk or recurrence: a meta-analysis. Breast Cancer Res Treat 2010, 119:477-484.
  6. Khan N, Adhami VM, Mukhtar H. Review: green tea polyphenols in chemoprevention of prostate cancer: preclinical and clinical studies. Nutr Cancer 2009, 61:836-841.
  7. Zheng J, Yang B, Huang T, et al. Green Tea and Black Tea Consumption and Prostate Cancer Risk: An Exploratory Meta-Analysis of Observational Studies. Nutr Cancer 2011:1-10.
  8. Kuriyama S, Shimazu T, Ohmori K, et al. Green tea consumption and mortality due to cardiovascular disease, cancer, and all causes in Japan: the Ohsaki study. JAMA 2006, 296:1255-1265.
  9. Iso H, Date C, Wakai K, et al. The relationship between green tea and total caffeine intake and risk for self-reported type 2 diabetes among Japanese adults. Ann Intern Med 2006, 144:554-562.
  10. Singh BN, Shankar S, Srivastava RK. Green tea catechin, epigallocatechin-3-gallate (EGCG): mechanisms, perspectives and clinical applications. Biochem Pharmacol 2011, 82:1807-1821.
  11. Pietta P, Simonetti P, Gardana C, et al. Relationship between rate and extent of catechin absorption and plasma antioxidant status. Biochem Mol Biol Int 1998, 46:895-903.
  12. Belcaro G, Ledda A, Hu S, et al. Greenselect phytosome for borderline metabolic syndrome. Evid Based Complement Alternat Med 2013, 2013:869061.
  13. Morre DM, Morre DJ. Catechin-vanilloid synergies with potential clinical applications in cancer. Rejuvenation Res 2006, 9:45-55.
  14. Singh S, Aggarwal BB. Activation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane) [corrected]. J Biol Chem 1995, 270:24995-25000.
  15. Sandur SK, Pandey MK, Sung B, et al. Curcumin, demethoxycurcumin, bisdemethoxycurcumin, tetrahydrocurcumin and turmerones differentially regulate anti-inflammatory and anti-proliferative responses through a ROS-independent mechanism. Carcinogenesis 2007, 28:1765-1773.
  16. Aggarwal BB. Nuclear factor-kappaB: the enemy within. Cancer Cell 2004, 6:203-208.
  17. Shoba G, Joy D, Joseph T, et al. Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Med 1998, 64:353-356.
  18. Mirzabeigi P, Mohammadpour AH, Salarifar M, et al. The Effect of Curcumin on some of Traditional and Non-traditional Cardiovascular Risk Factors: A Pilot Randomized, Double-blind, Placebo-controlled Trial. Iran J Pharm Res 2015, 14:479-486.
  19. Panahi Y, Alishiri GH, Parvin S, Sahebkar A. Mitigation of Systemic Oxidative Stress by Curcuminoids in Osteoarthritis: Results of a Randomized Controlled Trial. J Diet Suppl 2016, 13:209-220.
  20. Panahi Y, Hosseini MS, Khalili N, et al. Antioxidant and anti-inflammatory effects of curcuminoid-piperine combination in subjects with metabolic syndrome: A randomized controlled trial and an updated meta-analysis. Clin Nutr 2015, 34:1101-1108.
  21. Panahi Y, Rahimnia AR, Sharafi M, et al. Curcuminoid Treatment for Knee Osteoarthritis: A Randomized Double-Blind Placebo-Controlled Trial. Phytother Res 2014.
  22. Horigome S, Yoshida I, Ito S, et al. Inhibitory effects of Kaempferia parviflora extract on monocyte adhesion and cellular reactive oxygen species production in human umbilical vein endothelial cells. Eur J Nutr 2015.
  23. Nakata A, Koike Y, Matsui H, et al. Potent SIRT1 enzyme-stimulating and anti-glycation activities of polymethoxyflavonoids from Kaempferia parviflora. Nat Prod Commun 2014, 9:1291-1294.
  24. Shimada N. The safety and efficacy of Kamepferia parviflora extract (SIRTMAX®) on healthy volunteers. (Unpublished) 2012, http://maypro.com/products/sirtmax#_ednref1.
  25. Gu L, Kelm MA, Hammerstone JF, et al. Concentrations of proanthocyanidins in common foods and estimations of normal consumption. J Nutr 2004, 134:613-617.
  26. Xia EQ, Deng GF, Guo YJ, Li HB. Biological activities of polyphenols from grapes. Int J Mol Sci 2010, 11:622-646.
  27. Belcaro G, Ledda A, Hu S, et al. Grape seed procyanidins in pre- and mild hypertension: a registry study. Evid Based Complement Alternat Med 2013, 2013:313142.

Suggested Use

Take two capsules daily.

Supplement Facts

Serving Size 2 capsules

Servings Per Container 60

  Amount Per Serving % Daily Value
Curcumin C3 Complex® Turmeric Rhizome Extract (min. 95% Curcuminoids)500 mg*
GreenSelect® Phytosome™ (Green Tea Leaf Extract / Sunflower Phosphatidylcholine Complex)300 mg*
Turmeric Root200 mg*
ENOVITA® European Grape Seed Extract200 mg*
Sirtmax® Black Turmeric Rhizome Extract (Kaempferia parviflora)100 mg*
Cayenne Pepper Fruit (Capsicum annuun)12 mg*
Bioperine® Black Pepper Fruit Extract5 mg*

* Daily Value (DV) not established.

Other Ingredients

Hypromellose, vegetable stearic acid, silica.

Allergen Statement

(Made in a facility that also processes wheat products)

The products and statements made about specific products on this web site have not been evaluated by the United States Food and Drug Administration (FDA) and are not intended to diagnose, treat, cure or prevent disease. All information provided on this web site or any information contained on or in any product label or packaging is for informational purposes only and is not intended as a substitute for advice from your physician or other health care professional. You should not use the information on this web site for diagnosis or treatment of any health problem. Always consult with a healthcare professional before starting any new vitamins, supplements, diet, or exercise program, before taking any medication, or if you have or suspect you might have a health problem.